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5. Developmental changes or growth-related problems, such as Osgood-Schlatter disease, can cause pain in the growth area. According to StatPearls Publishing of the National Library of Medicine, the lifetime prevalence rate of Osgood-Schlatter disease is 9.8% in adolescents aged 12 to 15. This can be due to the fast bone growth that stretches the muscles and can be localized and tender to the touch.
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